Best Places to Work in Cleveland in 2025

Cleveland is a city full of opportunity, innovation, and heart. With its vibrant arts scene to foodie hotspots, there is plenty to enjoy. Pair that with a cost of living we can all get behind, and world-class healthcare. To sum it up, Cleveland offers the perfect balance of work and play. With a welcoming community and growing industries like healthcare, tech, and manufacturing, Cleveland is where big career moves meet a lifestyle that’s as interesting as you are.

10 Best Places to Work in Cleveland

OverDrive 

OverDrive digital platforms: Libby, Kanopy, and Sora are transforming how the world learns and accesses digital content, partnering with libraries and schools in 115+ countries to educate, entertain, and inspire through reading.

As a certified B Corporation, OverDrive isn’t just about business — it’s about making a positive impact. Their team of passionate innovators shares a love for books and a commitment to empowering communities through creativity, collaboration, and technology. From mentorship programs to wellness perks like fitness benefits and a fresh food market, OverDrive fosters a supportive environment where employees thrive. With OverDrive you can make a real difference while doing what you love. 

Keyfactor

Keyfactor is laser-focused on creating a hyper-connected world where every device, workload, and digital interaction is trusted and secure. As a global leader in cybersecurity, they empower enterprises to manage digital identities at scale, delivering peace of mind in an increasingly complex landscape. Keyfactor stands out for its "radical flexibility" with unlimited PTO, monthly company-wide days off, and comprehensive wellness initiatives. Whether you’re tuning into Talent Tuesdays or volunteering in your community, Keyfactor supports your growth, inside and outside of work. 

Axuall

Axuall applies big data to healthcare to enable seamless connections between technology and people to streamline inefficiencies and enhance the clinician and patient experience.

Recently named as one of the top startups and tech companies to watch in 2024, Axuall is making a real-world impact in healthcare. Their collaborative team thrives on curiosity and creativity, all while building tools that make a difference. With remote work options, unlimited PTO, fitness and professional development stipends, and stock options, Axuall ensures your individuality is celebrated as much as your career growth.

Felux

Felux is committed to the long-term success of the steel and metals industry, and they’re doing it from their Cleveland headquarters. With a focus on technology, data, and customer-first service, Felux is changing how steel and metal are sourced, procured, and distributed—making an age-old industry faster, smarter, and more accessible.

The tight-knit team at Felux team is laser-focused on making an impact, with a culture that values results, accountability, and a bit of fun along the way all while carving a path for the future of the steel industry.

Trailhead Biosystems

Trailhead Biosystems is focused on regenerative medicine with its proprietary HD-DoE® (High-Dimensional Design of Experiments) technology. Trailhead Biosystems is pushing the boundaries of stem cell engineering, transforming induced pluripotent stem cells (iPSCs) into virtually any desired cell type with unmatched precision by unlocking the precise cell states essential for human biology. As a pioneer in the rapidly growing field of regenerative medicine, employees are part of a visionary team dedicated to advancing biomedicine and inspiring future generations. With competitive salaries, 401(k) matching, full health benefits, and opportunities for professional growth in a cutting-edge, collaborative environment. 

airCFO

airCFO is on a mission to help startups thrive by managing their accounting, taxes, and financial operations with expertise and care. They’ve served over 300+ startups and mastered the art of making founders’ lives easier, so they can focus on building their businesses.

What makes airCFO a top workplace is its people-first culture. Just ask their team. “Last week, our Accounting & Finance Advisory team headed to Nashville for a Mini Offsite. We stepped away from our screens to focus on what matters most—our people. The energy in the room was incredible as we shared perspectives, strengthened connections, and explored how to better support each other and nurture the incredible culture we've built.” Their remote-first culture fosters flexibility and work-life balance, while perks like unlimited PTO, team retreats, and wellness stipends keep employees energized and supported. Add in opportunities for growth, networking, and working alongside some of the most innovative startups, and it’s clear why airCFO stands out as a place to grow, thrive, and connect.

Cleveland Clinic

Cleveland Clinic is more than a healthcare leader—it’s where brilliant minds come together to define the future of medicine. With a culture rooted in innovation and collaboration, this is a place where your ideas can shape patient care worldwide. Employees can expect world-class benefits plus endless opportunities for growth. Cleveland Clinic empowers its employees to thrive personally and professionally. 

Splash Financial

Splash Financial wants to make financial freedom attainable for everyone. From their Cleveland roots, Splash has grown into a national leader in student loan refinancing, helping people save money and conquer debt. Their hybrid marketplace model connects borrowers with the best rates from small banks and credit unions often overlooked.

With a remote-first culture, flexible PTO, equity opportunities, and quarterly meet-ups, Splash fosters creativity and connection while making a big impact on people’s lives. 

Centerline Biomedical

Centerline Biomedical uses cutting-edge navigation technology to reduce radiation exposure in healthcare, which helps improve procedural accuracy. Guided by values like teamwork, integrity, and a passion for innovation, they’re creating a safer future for patients and caregivers alike. As one of Cleveland’s best places to work, Centerline Biomedical is all about collaboration and innovation, but also making sure their team doesn’t burn out with a commitment to work-life balance. Here, your ideas drive real change, and your contributions matter. 

Within3

Within3 developed the world’s first insights management platform, transforming how life science companies drive innovation and deliver life-changing results for patients. They combine advanced AI-powered analytics with virtual engagement tools to empower companies to prioritize patients while also accelerating groundbreaking research. As a globally distributed team, Within3 has mastered the art of creating a dynamic, inclusive culture where collaboration thrives. With generous PTO and professional development opportunities, Within3 offers a career where you can thrive while making an impact.

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